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Literature Cited




1. J. R. Lancaster, jr., R. J. Hill, and W. G. Struve (1975) "The Character-ization of Energized and 


Partially De‐Energized (Respiration‐-Independent) β‐Galac-toside Transport in Escherichia coli" 


Biochim. Biophys. Acta 401, 285-298.


2. J. R. Lancaster, jr. and P. C. Hinkle (1977) "Studies of the β‐Galacto-side Transporter 


in Inverted Membrane Vesicles of E. coli. I. Symmetrical Facilitated Diffusion and Proton 


Gradient‐Coupled Trans-port" J. Biol. Chem. 252, 7657-7661.


3. J. R. Lancaster, jr. and P. C. Hinkle (1977) "Studies of the β‐Galacto-side Transporter in 


Inverted Membrane Vesicles of E. coli. II. Symmetrical Binding of a Dansylgalactoside Induced 


by an Electrochemical Proton Gradient and by Lactose Efflux" J. Biol. Chem. 252, 7662-7666. 


4. J. R. Lancaster, jr. (1978) "Site‐Exposure Model for Proton‐Lactose Symport in E. coli" J. 


Theor. Biol. 75, 35-50. 


5. J. R. Lancaster, jr. (1982) "Mechanism of Lactose‐Proton Cotran-sport in E. coli: Kinetic 


Results in Terms of the Site Exposure Model" FEBS Lett. 150, 9-18


6. J. R. Lancaster, jr., J. Vega, H. Kamin, N. Orme‐Johnson, W. H. Orme--Johnson, R. Krueger, 


and L. M. Siegel (1979) "Identification of the Iron--Sulfur Center of Spinach Ferredoxin‐Nitrite 


Reductase as a Tetranuclear Center, and Prelimi-nary EPR Studies of Mechanism" J. Biol. Chem.


7. J. R. Lancaster, jr., C. J. Batie, H. Kamin, and D. B. Knaff (1982) "Purifi-cation of Spinach Nitrite 


Reductase" In: Methods in Chloroplast Molecular Biology (M. Edelman, R. B. Hallick, and N. H. 


Chua,eds.) pp 723‐734. 


8. D. W. Seybert, J. R. Lancaster, jr., J. D. Lambeth, and H. Kamin (1979) "Partici-pation of the 


Membrane in Side‐Chain Cleavage of Cholesterol. Recons-titution of Cytochrome P450scc


Adrenal Cortex Mitochondria into Phospho-lipid Vesicles" J. Biol. Chem. 254, 12088-12098. 


9. J. D. Lambeth, J. R. Lancaster, jr., D. W. Seybert, and H. Kamin (1980) "Binding of Cholesterol 


and Adrenodoxin to Phospholipid Vesicle Reconstitu-ted P450scc" In: Microsomes, Drug 


Oxidations, and Chemical Carcinogenesis" (M. J. Coon, A. W. Conney, R. W. Estabrook, H. V. 


Gelboin, J. R. Gillette, and P. J. O'Brien, eds.) pp 553‐557.


10. J. D. Lambeth, J. R. Lancaster,jr., and H. Kamin (1981) "Steroido-genic Electron Transport by 


Adrenodoxin Reductase and Adrenodoxin: Use of Acety-lated Cytochrome c as a Mechanistic 


Probe of Electron Transfer" J. Biol. Chem. 256, 3674-3678.


11. J. D. Lambeth, D. W. Seybert, J. R. Lancaster, jr., J. C. Salerno and H. Kamin (1982)


 "Steroidogenic Electron Transport in Adrenal Cortex Mitochon-dria" Molec. Cell. Biochem. 45, 


12. H. Kamin, C. Batie, J. D. Lambeth, J. Lancaster, L. Graham, and J. C. Salerno (1985)


 "Paramagnetic Probes of Multicomponent Electron‐Tran-sfer Systems", Biochem. Soc. Trans.


13. J. R. Lancaster, jr. (1980) "Soluble and Membrane‐Bound Paramagnetic Centers in 


Methanobacterium bryantii" FEBS Lett. 115, 285-288.


14. J. R. Lancaster, jr. (1982) "New Biological Paramagnetic Center: Octahed-rally Coordinated 


Ni(III) in the Methanogenic Bacteria" Science 216, 1324-1325.


15. J. R. Lancaster, jr. (1982) "Identification and Detection of Electron Transfer Components in 


Methanogens" Meth. Enz. 88, 412-417.


16. A. J. Thomson (1982) “Proteins Containing Nickel” Nature 298. 602-603


17. J. R. Lancaster, jr. (1988) "The Bioinorganic Chemistry of Nickel", Editor, VCH Publishers.


18. D. J. Ecker, J. R. Lancaster, jr., and T. Emery (1982) "Siderophore Iron Transport Followed by 


Electron Paramagnetic Resonance Spectros-copy" J. Biol. Chem. 257, 8623-8626.


19. J. R. Lancaster, jr. (1981) "Membrane‐Bound Flavin Adenine Dinucleotide in 


Methanobacterium bryantii" Biochem. Biophys. Res. Comm. 100, 240-246.


20. T. W. Kirby, J. R. Lancaster, jr., and I. Fridovich (1981) "Isola-tion and Characterization of 


the Iron‐Containing Superoxide Dismutase of Methanobac­terium bryantii" Arch. Biochem. 


Biophys. 210, 140-148.


21. J. R. Lancaster, jr., K. Gillies, and K. R. Rogers (1985) "Bioener-getic Role of Nickel‐containing 


Proteins in Methano-gens" Rev. Port. Quim. 27, 73-75. 


22. B. P. Crider, S. W. Carper, and J. R. Lancaster,jr. (1985) "Electron Transfer‐Driven ATP 


Synthesis in Methanococcus voltae is Not Dependent on a Proton Electrochemical Gradient", 


Proc. Natl. Acad. Sci. USA 82, 6793-6796.


23. J. R. Lancaster, jr. (1986) "A Unified Scheme for Carbon and Electron Flow Coupled to ATP 


Synthesis by Substrate Level Phosphoryla-tion in the Methanogenic Bacteria" FEBS Lett. 199, 


24. S. W. Carper and J. R. Lancaster, jr. (1986) " An Electrogenic Sodium‐-translocating ATPase in 


Methanococcus voltae", FEBS Lett. 200, 177-180


25. H. A. Al‐Mahrouq, S. W. Carper, and J. R. Lancaster, jr. (1986) "Dis-crimination Between 


Transmembrane Ion Gradient‐Driven and Electron Transfer--Driven ATP Synthesis in the 


Methanogenic Bacteria", FEBS Lett. 207, 262-265.


26. J. R. Lancaster, jr.,S. W. Carper, B. P. Crider, K. Gillies, and K. R. Rogers (1986) "Bioenergetic 


Role of Nickel‐containing Proteins in Methano-gens", in Frontiers in Bioinorganic Chemistry, A. 


V. Xavier, ed., VCH Publishers, pp. 27-35.


27. K. R. Rogers, K. Gillies, and J. R. Lancaster, jr. (1988) "Iron-Sulfur Centers Involved in Electron 


Transfer in Methanobacterium thermoautotrophicum" Biochem. Biophys. Res. Comm. 153, 87-


28. J. R. Lancaster, jr. (1987) "ATP Synthesis and Ion Gradients in the Methano-genic Bacteria"


in Advances in Membrane Biochemistry and Bioener­getics, C. H. Kim, H. Tedeschi, J. J. Diwan, 


and J. C. Salerno, eds., Plenum Press, pp. 363-387.


29. J. R. Lancaster, jr. (1989) "Sodium, Protons, and Energy Coupling in the Methanogenic 


Bacteria" J. Bioenerg. Biomemb. 21, 717-740 (invited review).


30. D. Reddy, J. R. Lancaster, jr., and D. P. Cornforth (1983) "Nitrite Inhibition of Clostridium 


botulinum: Electron Spin Resonance Detection of Iron‐Nitric Oxide Complexes" Science 221, 


31. J. R. Lancaster, jr., S. M. Laster, and L. R. Gooding (1989) "Inhibition of Target Cell 


Mitochondrial Electron Transfer by Tumor Necrosis Factor" FEBS Lett. 248, 169-174.


32. J. R. Lancaster, jr., and J. B. Hibbs, jr., (1990) "EPR Demonstration of Iron-Nitrosyl Complex 


Formation by Cytotoxic Activated Macrophages", Proc. Natl. Acad. Sci. USA, 87, 1223-1227.


33. J. R. Lancaster, Jr., J. M. Langrehr, H.A. Bergonia, N. Murase, R. L. Simmons, and R. A. 


Hoffman (1992) “EPR Detection of Heme and Nonheme Iron-Containing Protein Nitrosylation by 


Nitric Oxide during Rejection of Rat Heart Allograft”, J. Biol. Chem. 267, 10994-10998.


34. J. M. Langrehr, A.R. Müller, H. Bergonia, T. Jacobs, W.H. Schraut, J. R. Lancaster, Jr., R.A. 


Hoffman, and R. L. Simmons (1992) “Detection of Nitric Oxide by EPR Spectroscopy During 


Rejection and Graft-Versus-Host Disease Following Small Bowel Transplantation in the Rat” 


Surgery 112, 395-402.


35. J. A. Corbett, J. R. Lancaster, jr., M. A. Sweetland, and M. L. McDaniel (1991) “Interleukin-


1β-induced Formation of EPR-Detectable Iron-Nitrosyl Complexes in Islets of Langerhans. Role 


of Nitric Oxide in Interleukin-1β-induced Inhibition of Insulin Secretion” J. Biol. Chem. 266, 


36. J. A. Corbett, R. G. Tilton, K. Chang, K. S. Hasan, Y. Ido, J. L. Wang, M. A. Sweetland, J. R. 


Lancaster, Jr., J. R. Williamson, and M. L. McDaniel (1992) “Aminoguanidine, a Novel Inhibitor of 


Nitric Oxide Formation, Prevents Diabetic Vascular Dysfunction” Diabetes 41, 552-556.


37. L. J. Nixon-Heiss, J. R. Lancaster, Jr., J. A. Corbett, and W. E. Goldman (1994) “Epithelial 


Autotoxicity of Nitric Oxide: Role in the Respiratory Cytopathology of Pertussis”, Proc. Natl. 


Acad. Sci. USA 91, 267-270.


38. J. Stadler, H. A. Bergonia, M. Di Silvio, M. A. Sweetland, T. R. Billiar, R. L. Simmons, and J. R. 


Lancaster, Jr. (1993) “Nonheme Iron-Nitrosyl Complex Formation in Rat Hepatocytes: Detection 


by Electron Paramagnetic Resonance Spectroscopy” Arch. Biochem. Biophys. 302, 4-11.


39. J. R. Lancaster, Jr., G. Werner-Felmayer, and H. Wachter (1994) “ Coinduction of Nitric Oxide 


Synthesis and Intracellular Nonheme Iron-Nitrosyl Complexes in Murine Cytokine-Treated 


Fibroblasts” Free Rad. Biol. Med. 16, 869-870.


40. MS Joshi, JL Ponthier, and JR Lancaster, Jr. (1999) “Cellular Antioxidant and Prooxidant 


Actions of Nitric Oxide” Free Rad. Biol. Med. 27, 357-1366.


41. Y-M. Kim, H. Bergonia, J. R. Lancaster, Jr. (1995) “Nitrogen Oxide-Induced Autoprotection in 


Isolated Rat Hepatocytes” FEBS Lett 374, 228-232.


42. Y-M. Kim, H. A. Bergonia, B. R. Pitt, W. D. Watkins, and J. R. lancaster, Jr. “Loss and 


Degradation of Enzyme-Bound Heme Induced by Cellular Nitric Oxide Synthesis” J. Biol. Chem.


43.Y-M. Kim, H. A. Bergonia, C. M. Müller, B. R. Pitt, W. D. Watkins, and J. R. Lancaster, Jr. 


(1995) “Nitric Oxide and Intracellular Heme” Adv. Pharmacol. 34:277-291.


44. M. A. Schwarz, J. S. Lazo, J. C. Yalowich, W. P. Allen, M. Whitmore, H. A. Bergonia, Lancaster, 


Jr. (1995) “Metallothionein Protects Against the Cytotoxic and DNA Damaging Effects of Nitric 


Oxide” Proc. Natl. Acad. Sci. USA 92, 4452-4456.


45. 33. Y-M Kim, JR Lancaster, Jr. (1993) “Tetrahydrobiopterin-Dependent Nitrite Oxidation to 


Nitrate in Isolated Rat Hepatocytes” FEBS Lett. 332: 255-259.


46. J. R. Lancaster, Jr. (1992) “Nitric Oxide in Cells” American Scientist 80:248-259


47. J. R. Lancaster, Jr. (1994) “ Simulation of the Diffusion and Reaction of Endogenously 


Produced Nitric Oxide” Proc. Natl. Acad. Sci. USA 91:8137-8141.


48. J. R. Lancaster, Jr. (1996) “Diffusion of Free Nitric Oxide” Meth. Enz. 268:31-50


49. J. R. Lancaster, Jr. “A Tutorial on the Diffusibility and Reactivity of Free Nitric Oxide” Nitric 


50. JR Lancaster, jr. (2000) “The Physical Properties of Nitric Oxide: Determinants of the 


Dynamics of NO in Tissue. in Nitric Oxide: Biology and Pathobiology Ignarro, LJ, ed. Academic 


Press, San Diego, CA pp 209-224


51. X. Liu, M.J. S. Miller, M. S. Joshi, H. Sadowska-Krowicka, D. A. Clark, and J. R. Lancaster, 


Jr. (1998) “Diffusion-Limited Reaction of Free Nitric Oxide with Erythrocytes” J. Biol. Chem.


52. J. R. lancaster, Jr. Sickle Cell Disease: Loss of the Blood’s WD40? Trends Pharmacol. Sci.


53. DD Thomas, X Liu, SP Kantrow, JR Lancaster, Jr. (2001) “The Biological Lifetime of Nitric 


Oxide: Implications for the Perivascular Dynamics of NO and O2” Proc. Natl. Acad. Sci. USA 98:


54. Joshi, MS, Ferguson, Jr., TB, Han, TH, Hyduke, DR, Liao, JC, Rassaf, T, Bryan, N, Feelisch, 


M, and Lancaster, Jr., JR “Nitric Oxide is Consumed, Rather than Conserved, by Reaction with 


Oxyhemoglobin under Physiological Conditions”. Proc. Natl. Acad. Sci. USA 99:10341-10346 


55. Gladwin, MT, Lancaster, Jr., JR, Freeman, BA, & Schechter, AN “Nitric Oxide Reactions with 


Hemoglobin: A View Through the SNO-Storm”. Nature Med 9:496-500 (2003).


56. X. Liu, M. J. S. Miller, M. S. Joshi, D. D. Thomas, and J. R. Lancaster, Jr. (1998) “Accelerated 


Reaction of Nitric Oxide with O2 within the Hydrophobic Interior of Biological Membranes” 


Proc. Natl. Acad. Sci. USA 95:2175-2179.


57. M. N. Möller, Q. Li, D. A. Vitturi, J. M. Robinson, J. R. Lancaster Jr., and A. Denicola (2007) 


“Membrane ‘Lens’ Effect: Focusing the Formation of Reactive Nitrogen Oxides from the •NO/O2


Reaction” Chem. Res. Toxicol. 20:709­714


58. J. C. Toledo, C. A. Bosworth, S. W. Hennon, and J. R. Lancaster, Jr. (2008) “Nitric Oxide-


Induced Conversion of Cellular Chelatable Iron into Macromolecule-Bound Dinitrosyliron 


Complexes” J. Biol Chem. 2008;283:2892659.


59. Lancaster, Jr., JR (2006) “Nitroxidative, Nitrosative, and Nitrative Stress: Kinetic Predictions 


of Reactive Nitrogen Species Chemistry Under Biological Conditions” Chem. Res. Toxicol.


60. Dinitrosyliron complexes and the mechanism(s) of cellular protein nitrosothiol formation 


from nitric oxide. Bosworth CA, Toledo JC Jr, Zmijewski JW, Li Q, Lancaster JR Jr. Proc Natl Acad 


Sci U S A. 2009;106:4671.


61. Q. Li, C. Li, H.K. Mahtani, J. Du, A.R. Patel, J.R. Lancaster Jr. “Nitrosothiol Formation and 


Protection against Fenton Chemistry by Nitric Oxide-Induced Dinitrosyliron Complex Formation 


from Anoxia-Initiated Cellular Chelatable Iron Increase” J. Biol. Chem. 2014 in press.


62. J. R. Lancaster, Jr., L. J. Ignarro, Free Rad. Biol. Med. 25:384


63. J. M. Langrehr, R. A. Hoffman, J. R. Lancaster, Jr., and R. L. Simmons (1993) “Nitric Oxide: A 


New Endogenous Immunomodulator” Transplantation 55:1205-1212


64. C. H. Evans, M. Steanovic-Racic, and J. R. Lancaster, Jr. (1995) “Nitric Oxide and its Role in 


Orthopaedic Disease” Clin. Orthop. Rel. Res. 312:275-294.


65. J. F. Kerwin, Jr., J. R. Lancaster, Jr., and P. L. Feldman (1995) “Nitric Oxide: A New Paradigm 


for Second Messengers” J. Med. Chem. 38:4343-4362.


66. J. B. Hibbs, Jr., R. R. Taintor, Z. Vavrin, D. L. Granger, J-C. Drapier, I. J. Amber, and J. R. 


Lancaster, Jr. (1990) “Synthesis of Nitric Oxide from a Terminal Guanidino Nitrogen Atom of L-


Arginine: a Molecular Mechanism Regulating Cellular Proliferation that Targets Intracellular 


Iron” in Nitric Oxide from L-Arginine: a Bioregulatory System Moncada, S, & Higgs, EA, eds., 


Elsevier pp189-223


67. P. D. Freeswick, D. A. Geller, J. R. Lancaster, Jr., and T. R. Billiar (1994) “Nitric Oxide and 


the Liver” in The Liver: Biology and Pathobiology 3rd ed. Arias I,Boyer J, Fausto N, Jakoby W, 


Schachter D, Shafritz D, eds, Raven Press, New York, NY pp 1031-1045


68. J. R. Lancaster, Jr. (1994) “The Biology of Nitric Oxide” in Encyclopedia of Inorganic 


Chemistry King RB, ed., Wiley pp 2482-2498


69. Y-M. Kim, T. R. Billiar, and J. R. Lancaster, Jr. “Reactive Oxygen and Nitrogen Metabolites 


and Related Enzymes. Kim,Y-M, Billiar, TR, and Lancaster, JR Jr. Handbook of Experimental 


Immunology, 1999.


70. D. J. Singel, J. R. Lancaster, Jr. (1996) “EPR Spectroscopy and NO Biology”. In Methods in 


Nitric Oxide Research, Feelisch, M, Stamler, JS, eds., Wiley, NY pp 341-356.


71. J. R. Lancaster, Jr., and D. J. Stuehr (1996) “The Intracellular Reactions of Nitric Oxide in the 


Immune System and its Enzymatic Synthesis” in Nitric Oxide: Principles and Actions Lancaster JR 


Jr., ed., Academic Press, San Diego, CA pp139-175


72. M. S. Joshi, and J. R. Lancaster, Jr. (1997) “Free Radicals and Disease” in Encyclopedia of 


Human Biology, 2nd ed. Dulbecco R, ed., Academic Press, San Diego, CA pp 107-114


73. J. R. Lancaster, Jr. (1997) “Interaction of NO with Iron-dependent Enzymes” in Ernst 


Schering Research Foundation Workshops Lancaster, Jr., JR, & Parkinson, JF, eds., Springer, 


74. J. R. Lancaster, Jr., ed. (1996) “Nitric Oxide: Principles and Actions”, Academic Press.


75. J. R. Lancaster, Jr., and J. F. Parkinson (1997) “Nitric Oxide, Cytochromes P450, and Sexual 


Steroid Hormones”, Springer.

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